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・ ARAD (Sumerogram)
・ Arad (surname)
・ Arad Administrative Palace
・ Arad Alexander House
・ Arad Central Railway Station
・ Arachalur
・ Arachana
・ Arachchi
・ Arachchige Gunawardene
・ Arachchikattuwa Divisional Secretariat
・ Arachidamia
・ Arachidic acid
・ Arachidonate 12-lipoxygenase
・ Arachidonate 15-lipoxygenase
・ Arachidonate 5-lipoxygenase
Arachidonate 5-lipoxygenase inhibitor
・ Arachidonate 8-lipoxygenase
・ Arachidonate—CoA ligase
・ Arachidonic acid
・ Arachidonic acid 5-hydroperoxide
・ Arachidonoyl serotonin
・ Arachidonyl-2'-chloroethylamide
・ Arachidonylcyclopropylamide
・ Arachidyl alcohol
・ Arachis
・ Arachis archeri
・ Arachis batizocoi
・ Arachis cardenasii
・ Arachis correntina
・ Arachis diogoi


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Arachidonate 5-lipoxygenase inhibitor : ウィキペディア英語版
Arachidonate 5-lipoxygenase inhibitor
Arachidonate 5-lipoxygenase inhibitors are compounds that slow or stop the action of the arachidonate 5-lipoxygenase (5-lipoxygenase or 5-LOX) enzyme, which is responsible for the production of inflammatory leukotrienes. The overproduction of leukotrienes is a major cause of inflammation in asthma and allergic rhinitis.〔David L. Nelson, Michael M. Cox. ''Lehninger's Principles of Biochemistry, Fifth Edition''. W.H. Freeman and Co., 2008, p. 359.〕
Examples of 5-LOX inhibitors include drugs, such as meclofenamate sodium〔 and zileuton.〔
Some chemicals found in trace amounts in food, and some dietary supplements, also have been shown in inhibit 5-LOX, such as baicalein, caffeic acid,〔 curcumin,〔 hyperforin〔〔〔 and St John's wort.
==See also==

*Antileukotriene agents

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Arachidonate 5-lipoxygenase inhibitor」の詳細全文を読む



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